differential scanning fluorimetry Search Results


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Unchained Labs differential scanning fluorimetry
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Abbott Laboratories differential scanning fluorimetry
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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AstraZeneca ltd high throughput thermal shift/differential scanning fluorimetry assay astrazeneca fragment library
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Unchained Labs differential scanning fluorimetry uncle0330
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Novozymes limited nano differential scanning fluorimetry experiments
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Schircks Laboratories differential scanning fluorimetry bh4
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Proteros Biostructures nano differential scanning fluorimetry (nanodsf) assay
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
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Biacore differential scanning fluorimetry (dsf)
Developability assessment of antibody clones. Differential scanning <t>fluorimetry</t> analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.
Differential Scanning Fluorimetry (Dsf), supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Developability assessment of antibody clones. Differential scanning fluorimetry analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.

Journal: mAbs

Article Title: Heavy chain-only antibodies with a stabilized human VH in transgenic chickens for therapeutic antibody discovery

doi: 10.1080/19420862.2024.2435476

Figure Lengend Snippet: Developability assessment of antibody clones. Differential scanning fluorimetry analysis was performed on the selected anti-pgrn (a) and anti-NKp46 (b) Omni dAb antibodies in sdAb-Fc format that showed high melting temperature (T m ) and aggregation temperature (T agg ). AC-SINS was performed to assess self-association for the selected anti-pgrn and anti-NKp46 clones (c), with the positive reference (ficlatuzumab, veltuzumab, and trastuzumab) and negative reference (bococizumab and duligotuzumab) IgG antibodies with known low and high AC-SINS values, respectively. , The FDA-approved VHH-Fc antibody caplacizumab was also included as a reference for the sdAb-Fc format.

Article Snippet: Differential scanning fluorimetry (UNCLE-0330, Unchained Labs, Pleasanton, CA) was used for the assessment of the melting temperature (T m ) and aggregation temperature (T agg ) on selected NKp46 and PGRN antibody clones in sdAb-Fc format.

Techniques: Clone Assay